Stiff-person syndrome

Like other types of neurological disorders SPS affects your brain and spinal cord central nervous system. Stiff Person Syndrome SPS is an autoimmune and neurological disorder that can make the muscles in the torso and limbs alternate between rigidity and spasms.

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Muscle spasms can be so violent they can dislocate joints and even break bones.

. Stiff person syndrome is more likely seen in people with certain types of diseases including. SPS is characterized by fluctuating muscle rigidity in the trunk and limbs and a heightened sensitivity to stimuli such as noise touch and emotional distress which can set off muscle spasms. The cause of this extremely rare disease is still unknown.

But more people are affected than reported due to misdiagnoses. Stiff person syndrome SPS is a rare progressive syndrome that affects the nervous system specifically the brain and spinal cord. Certain cancers including breast lung kidney thyroid colon and Hodgkins lymphoma.

Stiff-person syndrome SPS is a rare and disabling central nervous system disorder with no satisfactory treatment. Muscular rigidity often fluctuates ie grows worse and then improves and usually occurs along with the muscle spasms. SPS is strongly correlated with autoimmune diseases and it is usual to find high titers of antibodies against acid decarboxylase GAD65.

Why Choose Johns Hopkins. Stiff person syndrome SPS is a very rare disease affecting only one or two people per million. Spasms can generate enough force to fracture bone.

Stiff person syndrome SPS is an autoimmune neurological disorder. Symptoms may include extreme muscle stiffness rigidity and painful spasms in the trunk and limbs severely impairing mobility. Stiff-person syndrome SPS also known as stiff-man syndrome SMS 1 is a rare neurologic disorder of unclear cause characterized by progressive rigidity and stiffness.

Autoimmune disorders including diabetes thyroiditis vitiligo and pernicious anemia. Stiff-person syndrome SPS is a rare neurological disorder with features of an autoimmune disease. The stiffness primarily affects the truncal muscles and is superimposed by spasms resulting in postural deformities.

It causes progressive muscle stiffness and painful spasms that can be triggered by a variety of things including sudden movement cold temperature or unexpected loud noises. Muscle rigidity sporadic muscle spasms and chronic muscle pain characterize SPS. Stiff person syndrome SPS is a neurological disease with autoimmune features.

Stiff-person syndrome SPS is a rare acquired neurological disorder characterized by progressive muscle stiffness rigidity and repeated episodes of painful muscle spasms. SPS is labeled as a rare disease. Symptoms include muscle spasms hyper-rigidity debilitating pain and chronic anxiety.

Stiff Person Syndrome Center

The Stiff Person Syndrome Research Foundation

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Stiff Person Syndrome With Evidence Of Nonspecific Focal Myositis Secondary To Sustained Muscle Contraction A Case Report Sciencedirect

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Axial Dystonia Mimicking Stiff Person Syndrome Balint 2016 Movement Disorders Clinical Practice Wiley Online Library

Stiff Person Syndrome And Gad Antibody Spectrum Disorders Gabaergic Neuronal Excitability Immunopathogenesis And Update On Antibody Therapies Springerlink